Publications

Selected Publications

  1. Identification of AgRP cells in the murine hindbrain that drive feeding. Bachor TP, Hwang E, Yulyaningsih E, Attal K, Mifsud F, Pham V, Vagena E, Huarcaya R, Valdearcos M, Vaisse C, Williams KW, Emmerson PJ, Xu AW. Mol Metab. 2024 Jan 19:101886.
  2. Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance. Douglass JD*, Ness KM*, Valdearcos M*, Wyse-Jackson A, Dorfman MD, Frey JM, Fasnacht RD, Santiago OD, Niraula A, Banerjee J, Robblee M, Koliwad SK, Thaler JP. Cell Metab. 2023 Sep 5;35(9):1613-1629.e8.*Co-first author.
  3. ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control of satiety and glucose homeostasis. Vagena E, Crneta J, Engstrom P, He L, Yulyaningsih, Korpel NL, Cheang RT, Bachor TP, Huang A, Michel G, Attal K, Berrios DI, Valdearcos M, Koliwad SK, Yi C, Xu AW. Science Signaling, 2022 May 10; 15 (733):eabj8204.
  4. Metabolic factors in the regulation of hypothalamic innate immune responses in obesity. Folick A. Cheang R, Valdearcos M and Koliwad SK. Exp Mol Med. 2022 Apr;54(4):393-402.
  5. Microglial lipid biology in the hypothalamic regulation of metabolic homeostasis. Folick A, Koliwad SK and Valdearcos M. Front Endocrinol. 2021 May 27:12:668396.
  6. Hypothalamic microglia as potential regulators of metabolic physiology. Valdearcos M, Myers MG, Koliwad SK. Nat Metab. 2019 Mar;1(3):314-320.
  7. Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Valdearcos M, Douglass JD, Robblee MM, Dorfman MD, Stifler DR, Bennett ML, Gerritse I, Fasnacht R, Barres BA, Thaler JP, Koliwad SK. Cell Metab. 2017 Jul 05; 26(1):185-197.e3.
  8. Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier. Yulyaningsih E, Rudenko IA, Valdearcos M, Dahlén E, Vagena E, Chan A, Alvarez-Buylla A, Vaisse C, Koliwad SK, Xu AW. Cell Rep. 2017 Jun 13; 19(11):2257-2271.
  9. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. Feng X, Valdearcos M, Uchida Y, Lutrin D, Maze M, Koliwad SK. JCI Insight. 2017 Apr 06; 2(7):e91229.
  10. Saturated Fatty Acids Engage an IRE1a-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells. Robblee MM, Kim CC, Porter Abate J, Valdearcos M, Sandlund KL, Shenoy MK, Volmer R, Iwawaki T, Koliwad SK. Cell Rep. 2016 Mar 22; 14(11):2611-23.
  11. Hypothalamic inflammation in the control of metabolic function. Valdearcos M, Xu AW, Koliwad SK. Annu Rev Physiol. 2015; 77:131-60.
  12. Leptin potentiates astrogenesis in the developing hypothalamus. Rottkamp DM, Rudenko IA, Maier MT, Roshanbin S, Yulyaningsih E, Perez L, Valdearcos M, Chua S, Koliwad SK, Xu AW. Mol Metab. 2015 Nov; 4(11):881-9.
  13. Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function. Valdearcos M, Robblee MM, Benjamin DI, Nomura DK, Xu AW, Koliwad SK. Cell Rep. 2014 Dec 24; 9(6):2124-38.

FULL LIST