Diabetes Seminar

The Diabetes Seminar Series is a weekly forum for trainees and faculty to present their research with the goal of stimulating new research ideas and promoting interdisciplinary collaboration. This seminar series also features regional, national and international distinguished speakers invited to present cutting-edge research in the field of diabetes. Every Friday at noon.

 

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2023

 

June 14, 2023

"Deciphering mechanisms of beta cell development and regeneration"

Heiko Lickert PhD, Director, Institute of Diabetes and Regeneration Research (IDR), Helmholtz Munich & Professor and Chair of Beta Cell Biology, Technical University Munich (TUM)

 

May 26, 2023

"CRISPR gene editing in primary human islet cells"

Romina Bevacqua PhD, Assistant Professor, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai

 

May 19, 2023

"Tracking cell interactions using intercellular barcode transfer"

Neil Tay PhD, Postdoc, McManus Lab

 

May 12, 2023

"Modeling Rare, Genetic Bone Diseases to Uncover the Role of Gs-GPCR and BMP Signaling in Mesenchymal Tissue Function"

Kelly Wentworth MD, Adjunct Assistant Professor, Division of Endocrinology, UCSF Medical Center at Zuckerberg San Francisco General Hospital

 

May 5, 2023

"Integrating Disparate Approaches in Immunotherapy Induced Endocrinopathies"

Zoe Quandt MD, Adjunct Assistant Professor, Division of Endocrinology, UCSF Medical Center

&

"Single-Cell Multi-Omic Roadmap of Human Fetal Pancreatic Development"

Sean de la O, Graduate Student, Sneddon & Knox Labs, Department of Cell and Tissue Biology

 

April 21, 2023

"The kidney regulates food intake and body weight"

Tony K.T. Lam PhD, Associate Director of Research, Banting & Best Diabetes Centre, University of Toronto

 

April 14, 2023

"Overcoming the Challenges of Graft Hypoxia: Lessons from Pancreatic Islet Transplantations"

Hirotake Komatsu MD PhD, Assistant Professor, Translational Research & Cellular Therapeutics, Arthur Riggs Diabetes & Metabolism Research Institute, City of Hope, Los Angeles CA

 

March 24, 2023

"Designing immune evasion strategies to protect stem cell-derived beta cells from immune destruction"

Audrey Parent PhD, Associate Adjunct Professor, Diabetes Center

 

 

March 10, 2023

"Modeling Type 1 Diabetes using stem cells and genetic engineering""

Roberto Gutierrez, Graduate Student, Department of Pharmacology & Therapeutics, University of Florida, Gainesville FL

 

 

February 24, 2023

"Cell-environment interactions during tissue maturation and disease"

Haiting Ma PhD, Postdoctoral Fellow, Whitehead Institute, MIT

 

February 17, 2023

"Decoding regulatory T cell identity to inform better regulatory T cell therapies"

Jennifer Umhoefer, Graduate Student, Marson Lab, Gladstone-UCSF Institute of Genomic Immunology

 

February 10, 2023

“Uncovering the mechanism of lysine beta-hydroxybutyrlation”

Emily Goldberg PhD, Assistant Professor, Physiology

 

February 3, 2023 - Joint Seminar with Stanford

"Integrated functional imaging of islet communication"

Mark Huising PhD, Professor, Neurobiology, Physiology and Behavior, University of California Davis

 

January 27, 2023

"Aire-dependent Insulin-reactive clones in NOD T1D"

Jennifer Smith PhD, Anderson Lab, Diabetes Center

 

January 20, 2023

"Extrathymic Aire-expressing cells support maternal-fetal tolerance"

Hong Sun PhD, Gardner Lab, Department of Surgery and Diabetes Center

 

January 13, 2023

"High-fat diet regimes alter pathophysiology in inflammatory skin disease"

Zewen (Owen) Jiang, Graduate Student, Krummel & Bapat Labs, Department of Pathology and Diabetes Center

 

2022

December 9, 2022

"Technologies to clonally track and measure engineered T cells"

Daniel Goodman PhD, Postdoctoral Fellow, Roybal Lab, Microbiology and Immunology 

 

December 2, 2022 - Joint with Stanford

"Sox9 regulates alternative splicing and pancreatic beta cell function"

Hasna Maachi, PhD Postdoc, Hebrok lab

 

November 18, 2022

"Engineering Synthetic Suppressor Cells for Targeted Immune Suppression"

Nish Reddy, Graduate Student, Integrative Program in Quantitative Biology, Lim Lab, Department of Cellular and Molecular Pharmacology, UCSF

 

November 4, 2022 - Joint with Stanford

"Imaging islet vascular remodeling to track Type1 Diabetes development”

Richard Benniger PhD, Associate Professor, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Center

 

October 28, 2022

"Parathyroid Transplantation to Improve Islet Engraftment"

Yani Peng, Visiting Graduate Student, Second Xiangya Hospital of Central South University at Tang lab

 

October 21, 2022 - Distinguished Speaker in Diabetes Research

"Islet Autoimmunity and Avenues for Prevention"

Anette-Gabriele Ziegler PhD, Director, Helmholtz Munich Institute of Diabetes Research, Germany

 

October 14, 2022

"Enhancing regulatory T cell therapy using an orthogonal IL2 system to restore immune tolerance in Type 1 Diabetes"

Alyssa Indart, Graduate Student, Tang lab

 

October 7, 2022 - Joint with Stanford 

"Loss of the Transcription Factor RREB1 Reduces Cellular Insulin Content and Alters Gene Expression in Pancreatic Beta Cells"

Nicole Krentz PhD, Postdoc, Gloyn Lab, Stanford

 

September 30, 2022

"Development of IRE1α modulators to spare ER-stressed beta cells in diabetes"

Luka Suzuki, MD, PhD, Postdoc, Papa Lab

 

September 23, 2022 

"Investigating mechanisms of Type 2 Diabetes in the liver: an iPSC-based microphysiological approach"

Marko Groeger PhD, Postdoc, Willenbring Lab, Department of Surgery 

 

September, 16, 2022

"Recovery of Invariant natural killer T-cells to eliminate senescence in the HFD mice" 

Yao Wang PhD, Postdoc, Bhushan Lab

 

September 9, 2022

"Engineering white adipose tissue to treat obesity”

Hai Nguyen PhD, Postdoc, Ahituv Lab, Department of Bioengineering, UCSF

 

May 27, 2022

"Short-term expression of MAFAWT or mutant MAFAS64F enhances glucose-stimulated insulin secretion from stem cell-derived ​beta cells"

Veronica Cochrane, PhD, Postdoc, Hebrok Lab

 

May 20, 2022

"Extrathymic Aire-Expressing Cells in Immune Tolerance"

Jay Gardner, MD, PhD, Assistant Professor, Diabetes Center & Department of Surgery

 

May 13, 2022

"Developing Islet Antigen-Specific Tregs for Therapy in Type 1 Diabetes”

Emilie Ronin PhD, Postdoc, Tang Lab

 

May 6, 2022 - Joint Seminar with Stanford

"Beta Cell and Immune Cell Interactions in Type 1 Diabetes: The SKAP2 Story"

Chester Chamberlain PhD, Assistant Researcher, German lab

 

April 29, 2022

"Extrathymic Aire-Expressing Cells as Inducers of Immune Tolerance"

Alexander Gupta MD, Resident, Gardner Lab

 

April 22, 2022 - Invited Professor

“Enhancing cell replacement therapy in T1D using biomaterials for manufacturing, transplantation, and immune protection"

Lonnie Shea PhD, Professor, Biomedical Engineering, University of Michigan

 

April 15, 2022

"Biomimetic platform for Beta Cell Replacement Therapy to Treat T1 Diabetes"

Bhushan Kharbikar PhD, Postdoc, Desai Lab

 

April 8, 2022

"Developing a Robust Immunologic Self-Representation Score for scRNAseq Analysis"

Joe Germino, Graduate student, Gardner & Ntranos Labs

 

April 1, 2022 - Visiting Professor, Joint Seminar with Stanford

"Pathogenetic implications of proinsulin mishandling"

Thomas Mandrup-Poulsen PhD, Professor, Biomedical Sciences, University of Copenhagen

 

March 18, 2022

"A New Player in Feeding Regulation"

Tomas Bachor PhD, Postdoc, Xu lab

 

March 11, 2022

"Insights into Immune Checkpoint Inhibitor Induced Endocrinopathies"

Zoe Quandt MD, Clinical Fellow, Anderson lab

 

February 25, 2022

"Elucidating Inflammation-induced Cell Fate Decisions in Primary Human Tregs"

Patrick Ho PhD, Postdoc, Tang Lab

 

February 18, 2022

"Primary cilia of Melanocortin-4 Receptor Neurons Regulates Body Weight"

Annie Yue, Graduate Student, Vaisse Lab

 

February 11, 2022 - Distinguished Speaker in Diabetes

"Deciphering Mechanisms of ß-Cell Development, Heterogeneity and Regeneration"

Heiko Lickert PhD, Director, Institute for Diabetes and Regeneration, Helmholtz Munich

 

January 28, 2022

"A tale of two APCs: MHCII-mediated antigen presentation by thymic stromal cells enforces central T-cell tolerance"

Irina Proekt, PhD, Postdoc, Anderson Lab

 

January 21, 2022

"Triporter - A novel multi-reporter transgenic mouse to track gene editing"

Wilson Poon PhD, Postdoc, McManus Lab 

 

January 14, 2022 - Distinguished Speaker in Diabetes Research

"Engineering Regulatory T cells for tolerance"

Megan Levings PhD, Children’s Hospital Research Institute, University of British Columbia

 

2021

 

November 19, 2021

"Osteocytic coordination of systemic energy balance and bone quality"

Tamara Alliston PhD, Professor, Orthopaedic Surgery, UCSF

 

November 12, 2021

“Beta cell senescence in Type 1 Diabetes: Lessons from culture models”

Peter Thompson PhD, Assistant Professor, Physiology & Pathophysiology, University of Manitoba

 

October 29, 2021 

“Tectonics of the foregut-midgut junction”

David Scheel, Specialist, German lab

 

October 22, 2021 - Distinguished Speakers in Diabetes

“The new biology of beta cell failure”

Domenico Accili MD, Director, Diabetes and Endocrinology Research Center, Columbia University

 

October 8, 2021

“Cell-interaction based CRISPR screening using intercellular barcode transfer”

 Neil Tay PhD, Postdoc, McManus lab

 

October 1, 2021

“Building an Implantable Bio-Artificial Pancreas”

Shuvo Roy PhD, Professor, Bioengineering and Therapeutic Sciences (BTS)

 

September 24, 2021

"Single-Cell Multiomics Defines Tolerogenic Extrathymic Aire-Expressing Populations with Unique Homology to Thymic Epithelium"

Jiaxi Wang, Graduate Student, Gardner Lab 

 

September 17, 2021

"Hypothalamic aging and metabolic impairment"

Viana Pham, Graduate Student, UC Berkeley Nutritional Sciences & Toxicology at Xu lab

 

September 10, 2021

"100 years of Insulin"

Mike German MD, Professor, Diabetes Center 

 

June 3, 2021

"Clic-like chloride channel-1 (Clcc1) regulates insulin secretion in beta cells"

Yaohuan Zhang, Graduate Student, Ku lab

 

May 20, 2021

"Development of a scalable method for production and purification of beta cells with enhanced function"

Sudipta Ashe PhD, Postdoc, Hebrok lab

 

May 13, 2021

"New perspective on the leptin-Melanocortin system: MC4R regulation of energy homeostasis depends on neuronal primary cilia"

Adelaide Bernard, Graduate student, Metabolic Biology, UC Berkeley, at Vaisse lab

 

May 6, 2021

"Tuning the immune response to senescent beta cells"

Anil Bhushan PhD, Professor, Diabetes Center

 

April 29, 2021

"Maturation of Stem Cell Derived Beta Cells"

Holger Russ PhD, Assistant Professor, Barbara Davis Center for Diabetes, University of Colorado Denver

 

March 25, 2021

"Illuminating the dark druggable genome"

Olga Gulyaeva PhD, Postdoc, McManus Lab

 

March 11, 2021

"Towards Precision Genetics for Type 1 Diabetes"

Chester Chamberlain PhD, Assistant Researcher, German lab

 

March 4, 2021

"Crossing the valley of death - translating discoveries into therapies for T1D"

Qizhi Tang PhD, Professor, Department of Surgery

 

February 25, 2021

"CNS Circuits in Regulation of Satiety"

Allison Xu PhD, Professor, Diabetes Center

 

February 18, 2021

"Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks"

Jacob Freimer PhD, Postdoc, Marson lab (joint postdoc with Pritchard lab, Stanford)

 

February 4, 2021

"Designing the next generation of chimeric antigen receptors for regulatory T cell therapy"

Leonardo Ferreira PhD, Postdoc, Bluestone lab

 

January 14, 2021

"Utilizing syngeneic NOD tumor models to profile anti-tumor immunity and immunotoxicity"

Arabella Young PhD, Postdoc, Bluestone Lab

 

December 17, 2020

"Isoform-level single cell analysis with Transcript Compatibility Counts"

Vasilis Ntranos PhD, Assistant Professor, Bioinformatics, Diabetes Center

 

December 10, 2020

"Investigating the Role of the Mitochondrial Iron-Sulfur Cluster Protein BOLA3 in Beta Cell Metabolism and Function"

Natanya Kerper, Graduate Student, Hebrok Lab

 

December 3, 2020

"Exploring the CAR co-stimulation landscape: Pooled screening of CAR-T variants identifies novel signaling domains for next-generation immunotherapies"

Daniel Goodman, PhD, Postdoc, Bluestone lab (co-advised by Alex Marson and Kole Roybal)

 

November 19, 2020

"Single-cell transcriptional profiling of the human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla"

Audrey Parent PhD, Adjunct Assistant Professor, Diabetes Center

 

November 12, 2020

"Microglia Mediate Neonatal Weight Gain and Early-Life Programming of Adult Glucose Control"

Martin Valdearcos PhD, Adjunct Assistant Professor, Diabetes Center

 

October 22, 2020

"Single cell resolution of homeostatic murine pancreatic duct heterogeneity"

Audrey Hendley PhD, Postdoc, Weaver lab

 

October 15, 2020

Sagar Bapat MD PhD, Research Fellow, Diabetes Center

 

October 8, 2020

"Human pancreatic development at single-cell resolution: in vivo characterization to in vitro culture"

Zhe Liu PhD, Postdoc, Sneddon Lab

 

September 24, 2020

"Using outliers to unravel autoimmunity"

Mark Anderson MD PhD, Professor, Diabetes Center

 

September 17, 2020

"Tapping adipogenic progenitors to tip the balance between beige and fibrotic fat"

Suneil Koliwad MD PhD, Chief, Division of Endocrinology

 

September 10, 2020

"Serotonin 1F receptor (HTR1F) regulates primary human beta cell survival during transplant"

Deeksha Gambhir PhD, Postdoc, Ku lab

 

May 28, 2020

Sean De La O, Graduate Student, Sneddon Lab

 

May 21, 2020

"Identification and Characterization of Aire-dependent Tregs in T1D"

Jennifer Bridge PhD, Postdoc, Anderson Lab 

 

April 30, 2020  

Mike German MD, Professor, Diabetes Center

 

March 6, 2020

"Regulation of mucosal immune responses by integrins and TGF-beta"

Mark Travis PhD, Manchester Collaborative Centre for Inflammation Research, University of Manchester