Publications

Chendke GS, Kharbikar BN, Ashe S, Faleo G, Sneddon JB, Tang Q, Hebrok M, Desai TA.  Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space. Bioeng Transl Med. 2023 May 19;8(4):e10520.
 
de la O S, Yao X, Chang S, Liu Z, Sneddon JB. Single-cell chromatin accessibility of developing murine pancreas identifies cell state-specific gene regulatory programs. Mol Metab. 2023 Jul;73:101735.
 
Barlow HR, Ahuja N, Bierschenk T, Htike Y, Fassetta L, Azizoglu DB, Flores J, Gao N, De la O S, Sneddon JB, Marciano DK, Cleaver O. Rab11 is essential to pancreas morphogenesis, lumen formation and endocrine mass. Dev Biol. 2023 Jul;499:59-74.
 
Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB. Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. iScience. 2023 Mar 25;26(4):106500.
 
de la O S, Liu Z, Sun H, Yu SK, Wong DM, Chu E, Rao SA, Eng N, Peixoto G, Bouza J, Shen Y, Knox SM, Tward AD, Gloyn AL, Sneddon JB. Single-cell multi-omic roadmap of human fetal pancreatic development. BioRxiv 480942 [Preprint]. February 17, 2022. Available from https://doi.org/10.1101/2022.02.17.480942.
 
Peaslee C, Esteva-Font C, Su T, Munoz-Howell A, Duwaerts CC, Liu Z, Rao S, Liu K, Medina M, Sneddon JB, Maher JJ, Mattis AN. Doxycycline significantly enhances induction of induced pluripotent stem cells to endoderm by enhancing survival through protein kinase B phosphorylation. Hepatology 2021 Oct;74(4):2102-2117.
 
Migliorini A, Nostro MC, Sneddon JB. Human pluripotent stem cell-derived insulin-producing cells: A regenerative medicine perspective. Cell Metab. 2021 Apr 6;33(4):721-731.
 
Bautista JL, Cramer NT, Miller CN, Chavez J, Berrios DI, Byrnes LE, Germino J, Ntranos V, Sneddon JB, Burt TD, Gardner JM, Ye CJ, Anderson MS, Parent AV. Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla. Nat Commun. 2021 Fev 17;12(1):1096.
 
Frumm SM, Yu SK, Chang J, Artichoker JA, Scaria SM, Lee KP, Byrnes LE, Sneddon JB, Tward AD. A hierarchy of proliferative and migratory keratinocytes maintains the tympanic membrane. Cell Stem Cell. 2021 Feb 4;28(2):315-330.
 
Rust K, Byrnes LE, Yu KS, Park JS, Sneddon JB, Tward AD, Nystul TG. A single-cell atlas and lineage analysis of the adult Drosophila ovary. Nat Commun. 2020 Nov 6;11(1):5628.
 
Patzek S, Sneddon JB. Beta Living through Alpha Cells. Cell Stem Cell. 2019 Apr 4;24(4):503-505. doi: 10.1016/j.stem.2019.03.016. 
 
Liu Z, Sneddon JB. Pancreatic development: one cell at a (pseudo)time. EMBO J. 2019 Apr 15;38(8):e101891. doi: 10.15252/embj.2019101891. Epub 2019 Mar 26. 
 
Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB. Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun. 2018 Sep 25;9(1):3922. doi: 10.1038/s41467-018-06176-3.
 
Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 Oct 1;128(10):4343-4358. doi: 10.1172/JCI99435.
 
Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 2018 Jun 1;22(6):810-823. doi: 10.1016/j.stem.2018.05.016.
 
Farmer DT, Nathan S, Finley JK, Shengyang Yu K, Emmerson E, Byrnes LE, Sneddon JB, McManus MT, Tward AD, Knox SM. Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Development. 2017 Jul 1;144(13):2517-2528. doi: 10.1242/dev.150789. Epub 2017 Jun 2.
 
Cheng CW, Villani V, Buono R, Wei M, Kumar S, Yilmaz OH, Cohen P, Sneddon JB, Perin L, Longo VD. Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. Cell. 2017 Feb 23;168(5):775-788.e12. doi: 10.1016/j.cell.2017.01.040. 
 
Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA. Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells. Stem Cells. 2013 Dec;31(12):2833-41. doi: 10.1002/stem.1445. 
 
Sneddon JB, Borowiak M, Melton DA. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 2012 Nov 29;491(7426):765-8. doi: 10.1038/nature11463. Epub 2012 Oct 7. 
 
Sneddon JB. The contribution of niche-derived factors to the regulation of cancer cells. Methods Mol Biol. 2009;568:217-32. doi: 10.1007/978-1-59745-280-9_14.
 
Sneddon JB, Werb Z. Location, location, location: the cancer stem cell niche. Cell Stem Cell. 2007 Dec 13;1(6):607-11. doi: 10.1016/j.stem.2007.11.009.
 
Welm AL, Sneddon JB, Taylor C, Nuyten DS, van de Vijver MJ, Hasegawa BH, Bishop JM. The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7570-5. doi: 10.1073/pnas.0702095104.
 
Scharpf RB, Iacobuzio-Donahue CA, Sneddon JB, Parmigiani G. When should one subtract background fluorescence in 2-color microarrays? Biostatistics. 2007 Oct;8(4):695-707. doi: 10.1093/biostatistics/kxl041. Epub 2006 Dec 12.
 
Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse HJ, Bartelink H, Brown PO, Chang HY, van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Res. 2006;8(5):R62. doi: 10.1186/bcr1614. 
 
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14842-7. doi: 10.1073/pnas.0606857103. Epub 2006 Sep 26. 
 
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3738-43. doi: 10.1073/pnas.0409462102. Epub 2005 Feb 8.
 
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol. 2004 Feb;2(2):E7. doi: 10.1371/journal.pbio.0020007. Epub 2004 Jan 13.