Molecular mimicry in multisystem inflammatory syndrome in children. Aaron Bodansky, Robert C. Mettelman, Joseph J. Sabatino Jr, Sara E. Vazquez, Janet Chou, Tanya Novak, Kristin L. Moffitt, Haleigh S. Miller, Andrew F. Kung, Elze Rackaityte, Colin R. Zamecnik, Jayant V. Rajan, Hannah Kortbawi, Caleigh Mandel-Brehm, Anthea Mitchell, Chung-Yu Wang, Aditi Saxena, Kelsey Zorn, David J. L. Yu, Mikhail V. Pogorelyy, Walid Awad, Allison M. Kirk, James Asaki, John V. Pluvinage, Michael R. Wilson, Laura D. Zambrano, Angela P. Campbell, Overcoming COVID-19 Network Investigators, Paul G. Thomas, Adrienne G. Randolph, Mark S. Anderson & Joseph L. DeRisi. Nature. 07 August 2024
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases. Journal of Experimental Medicine. 2024 Nov 4;221(11):e20231152. doi: 10.1084/jem.20231152. Epub 2024 Oct 1
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. Nature. 2023 Nov; 623(7988):803-813. doi: 10.1038/s41586-023-06717-x. Epub 2023 Nov 8
Aire in Autoimmunity. Corey N Miller, Michael R Waterfield, James M Gardner, Mark S Anderson. Annual Review of Immunology. 2024 Jun;42(1):427-53. doi: 10.1146/annurev-immunol-090222-101050. Epub 2024 Jun 14.
Validation of a murine proteome-wide phage display library for identification of autoantibody specificities. Elze Rackaityte, Irina Proekt, Haleigh S. Miller, Akshaya Ramesh, Jeremy F. Brooks, Andrew F. Kung, Caleigh Mandel-Brehm, David Yu, Colin R. Zamecnik, Rebecca Bair, Sara E. Vazquez, Sara Sunshine, Clare L. Abram, Clifford A. Lowell, Gabrielle Rizzuto, Michael R. Wilson, Julie Zikherman, Mark S. Anderson, and Joseph L. DeRisi. JCI Insight. 2023 Dec 8;8(23):e174976. doi: 10.1172/jci.insight.174976.
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq. eLife 11:e78550.
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19. van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ; UCSF COMET consortium. Science Translational Medicine. 2021 Sep 22;13(612):eabh2624. doi: 10.1126/scitranslmed.abh2624. Epub 2021 Aug 24.PMID: 34429372
A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance. Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. Journal of Experimental Medicine. 2021 Aug 2;218(8):e20210759. doi: 10.1084/jem.20210759. Epub 2021 Jun 11.PMID: 34115115
Neutralizing Autoantibodies to Type I Interferons in COVID-19 Convalescent Donor Plasma. Vazquez SE, Bastard P, Kelly K, Gervais A, Norris PJ, Dumont LJ, Casanova JL, Anderson MS, DeRisi JL. Journal of Clinical Immunology. 2021 Aug;41(6):1169-1171. doi: 10.1007/s10875-021-01060-0. Epub 2021 May 19.PMID: 34009544
Autoimmune Endocrinopathies: An Emerging Complication of Immune Checkpoint Inhibitors. Quandt Z, Young A, Perdigoto AL, Herold KC, Anderson MS. Annual Review Medicine. 2021 Jan 27;72:313-330. doi: 10.1146/annurev-med-050219-034237. Epub 2020 Sep 4.PMID: 32886542
Tolerance in the Age of Immunotherapy. Bluestone JA, Anderson M. New England Journal of Medicine. 2020 Sep 17;383(12):1156-1166. doi: 10.1056/NEJMra1911109.PMID: 32937048
Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq. Vazquez SE, Ferré EM, Scheel DW, Sunshine S, Miao B, Mandel-Brehm C, Quandt Z, Chan AY, Cheng M, German M, Lionakis M, DeRisi JL, Anderson MS. Elife. 2020 May 15;9:e55053. doi: 10.7554/eLife.55053.PMID: 32410729
The Molecular Medicine Investigation Unit: Linking Patient Care and Scientific Inquiry in Physician-Scientist Training. Berger A, Matloubian M, Shah NP, Wachter RM, DeRisi JL, Anderson M. J Grad Med Educ. 2020 Feb;12(1):92-97. doi: 10.4300/JGME-D-19-00507.1.PMID: 32089799
New Frontiers in the Treatment of Type 1 Diabetes. Warshauer JT, Bluestone JA, Anderson MS. Cell Metabolism. 2020 Jan 7;31(1):46-61. doi: 10.1016/j.cmet.2019.11.017. Epub 2019 Dec 12.PMID: 31839487
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Nature. 2018 Jul;559(7715):627-631. doi: 10.1038/s41586-018-0345-2. Epub 2018 Jul 18.PMID: 30022164
Thymic tolerance as a key brake on autoimmunity. Cheng M, Anderson MS. Nature Immunology. 2018 Jul;19(7):659-664. doi: 10.1038/s41590-018-0128-9. Epub 2018 Jun 20.PMID: 29925986
Insights into immune tolerance from AIRE deficiency. Proekt I, Miller CN, Lionakis MS, Anderson MS. Current Opinion Immunology. 2017 Dec;49:71-78. doi: 10.1016/j.coi.2017.10.003. Epub 2017 Oct 21.PMID: 29065385
AIRE expands: new roles in immune tolerance and beyond. Anderson MS, Su MA. Nature Review Immunology. 2016 Apr;16(4):247-58. doi: 10.1038/nri.2016.9. Epub 2016 Mar 14.PMID: 26972725