Publications

1. In utero hematopoietic cell transplantation in fetuses with α-thalassemia major: a phase 1 clinical trial. Blood Adv. 2026 Jul 28; 10(14):5003-5013.MacKenzie TC, Lianoglou BR, Gonzalez Velez J, Dvorak CC, Kharbanda S, Herzeg A, Canepa E, Kreger EM, Frascoli M, Sper R, Gupta AR, Leung J, Tang Q, Sinha R, Worthington AK, Gano D, Bakkour Coco S, Chafets D, Keller RL, Shimotake J, Lal A, Glenn OA, Moon-Grady AJ, Vichinsky E.  PMID: 41984996; PMCID: PMC13382725.

2. Regulatory T cell modulation with selective CD28 blockade and IL-6 receptor antagonist in kidney transplant recipients: results of CTOT-24, a prospective clinical trial. Am J Transplant. 2026 Jul 22.Chandran S, Tang Q, Leung JC, Armstrong BD, Friedewald JJ, Kirk AD, Laszik ZG, Goldstein J, Morsheimer M, Vincenti FG.  PMID: 42486389.

3. Dual CD8 and TCR editing in regulatory T cells mediates HLA-A2-restricted tissue-specific homing. Mol Ther. 2026 Jun 03; 34(6):3388-3404.Porret R, Lebreton F, Pace E, Stefanidis E, Semilietof A, Guillaume P, Georgakis S, Alfageme-Abello O, Alcaraz-Serna A, Ermellino L, Cecchin R, Lana E, Hafezi M, Procopio F, Bellofatto K, Giordano Attianese GMP, Zoete V, Perreau M, Petrovas C, Irving M, Berishvili E, Tang Q, Muller YD.  PMID: 41709576; PMCID: PMC13239781.

4. Gene-corrected regulatory T cell therapy for IL2RA deficiency. Mol Ther. 2026 Mar 04; 34(3):1367-1381.Ha AS, Kalter N, Rosenberg M, Acevedo LA, Liang B, Liu W, Paruthiyil S, Sinha M, Vu A, Nguyen V, Qi Z, Krishnappa N, Shu J, Yu J, Catanzaro J, Bluestone JA, Tang Q, Urnov FD, Marson A, Hendel A, Herold KC, Shy BR, Esensten JH.  PMID: 41376159; PMCID: PMC12974163.

5. Pharmacokinetics, lineage identity, and trafficking of ex vivo expanded polyclonal regulatory T cells in a prospective randomized clinical trial of kidney transplant recipients with allograft inflammation. Am J Transplant. 2026 Apr; 26(4):744-759.Chandran S, Leung JC, Vu A, Lee K, Fitch M, Esensten JH, Shy BR, Putnam AL, Lares A, Acevedo LA, Nguyen V, Liu W, Armstrong B, Laszik ZG, Mannon RB, Friedewald JJ, Naik A, Davis S, Sarwal M, Hellerstein M, Morsheimer M, Goldstein J, Tang Q, Vincenti FG.  PMID: 41314617; PMCID: PMC12971219.

6. FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry. Immunity. 2026 Jan 13; 59(1):129-144.e13.Umhoefer JM, Arce MM, Kasinathan S, Whalen S, Dajani R, Subramanya S, Goudy L, Belk JA, Zhou R, Pham MTN, Zhang W, Hernandez R, Tran C, Kirthivasan N, Freimer JW, Mowery CT, Nguyen V, Ota M, Gowen BG, Simeonov DR, Curie GL, Li Z, Chen AY, Corn JE, Chang HY, Tang Q, Gilbert LA, Satpathy AT, Pollard KS, Marson A.  PMID: 41237776; PMCID: PMC12703790.

7. Ex Vivo Expanded Regulatory T Cells Inhibit AAA Progression by Limiting CD4+ and CD8+ T Cell Accumulation in Aortic Tissue. bioRxiv. 2025 Oct 10.Dasari C, Lopez JL, Jan MS, Shaligram S, Lin PY, Lévy-Lambert D, Huang AG, Valenzuela CL, Hadley P, Tang Q, Oskowitz A.  PMID: 41279653; PMCID: PMC12632420.

8. Face off: Stem cell therapy versus the immune system. Cell Stem Cell. 2025 Sep 04; 32(9):1318-1320.Castro-Gutierrez R, Tang Q.  PMID: 40912234.

9. Rebalancing the Immune System to Treat Type 1 Diabetes. Cold Spring Harb Perspect Med. 2025 08 01; 15(8).Muller YD, Ho P, Bluestone JA, Tang Q.  PMID: 39284666; PMCID: PMC12424549.

10. Advances in Cell Replacement Therapies for Diabetes. Diabetes. 2025 Jul 01; 74(7):1068-1077.Hering BJ, Rickels MR, Bellin MD, Millman JR, Tomei AA, García AJ, Shirwan H, Stabler CL, Ma M, Yi P, Luo X, Tang Q, Ramachandran S, Oberholzer J, Ricordi C, Kieffer TJ, Shapiro AMJ.  PMID: 40272266; PMCID: PMC12185959.

11. T cell receptor precision editing of regulatory T cells for celiac disease. Sci Transl Med. 2025 Mar 19; 17(790):eadr8941.Porret R, Alcaraz-Serna A, Peter B, Bernier-Latmani J, Cecchin R, Alfageme-Abello O, Ermellino L, Hafezi M, Pace E, du Pré MF, Lana E, Golshayan D, Velin D, Eyquem J, Tang Q, Petrova TV, Coukos G, Irving M, Pot C, Pantaleo G, Sollid LM, Muller YD.  PMID: 40106579.

12. Acquired immune tolerance 2. . Am J Transplant. 2025 May; 25(5):890-892.Tang Q.  PMID: 40057197.

13. Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead. Nat Rev Endocrinol. 2025 Jan; 21(1):14-30.Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler C, Brehm M, Papas K, Citro A, Shirwan H, Millman JR, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Ricordi C, Latres E, Mamrak NE, Giraldo J, Poznansky MC, de Vos P.  PMID: 39227741; PMCID: PMC11938328.

14. Harnessing regulatory T cells to establish immune tolerance. Sci Transl Med. 2024 03 13; 16(738):eadm8859.Ho P, Cahir-McFarland E, Fontenot JD, Lodie T, Nada A, Tang Q, Turka LA, Bluestone JA.  PMID: 38478632.

15. Precise surface functionalization of PLGA particles for human T cell modulation. Nat Protoc. 2023 11; 18(11):3289-3321.Hadley P, Chen Y, Cline L, Han Z, Tang Q, Huang X, Desai T.  PMID: 37853157; PMCID: PMC10775953.

16. Epidermal Stem Cell Derived Exosomes Alleviate Excessive Autophagy Induced Endothelial Cell Apoptosis by Delivering miR200b-3p to Diabetic Wounds. J Invest Dermatol. 2024 05; 144(5):1134-1147.e2.Xu H, Yang H, Wang Z, Tang Q, Cao X, Chen C, Dong Y, Xu Z, Lv D, Rong Y, Chen M, Tang B, Deng W, Zhu J, Hu Z.  PMID: 37838331.

17. Feasibility of an implantable bioreactor for renal cell therapy using silicon nanopore membranes. Nat Commun. 2023 08 29; 14(1):4890.Kim EJ, Chen C, Gologorsky R, Santandreu A, Torres A, Wright N, Goodin MS, Moyer J, Chui BW, Blaha C, Brakeman P, Vartanian S, Tang Q, David Humes H, Fissell WH, Roy S.  PMID: 37644033; PMCID: PMC10465514.

18. Regulatory T cells targeting a pathogenic MHC class II: Insulin peptide epitope postpone spontaneous autoimmune diabetes. Front Immunol. 2023; 14:1207108.Obarorakpor N, Patel D, Boyarov R, Amarsaikhan N, Cepeda JR, Eastes D, Robertson S, Johnson T, Yang K, Tang Q, Zhang L.  PMID: 37593744; PMCID: PMC10428008.

19. Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial. Am J Transplant. 2023 12; 23(12):1872-1881.Guinan EC, Contreras-Ruiz L, Crisalli K, Rickert C, Rosales I, Makar R, Colvin R, Geissler EK, Sawitzki B, Harden P, Tang Q, Blancho G, Turka LA, Markmann JF.  PMID: 37422112.

20. Regulatory T cells aid stem-cell therapy for Parkinson's disease. Nature. 2023 07; 619(7970):470-472.Tang Q.  PMID: 37438628.

21. Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space. Bioeng Transl Med. 2023 Jul; 8(4):e10520.Chendke GS, Kharbikar BN, Ashe S, Faleo G, Sneddon JB, Tang Q, Hebrok M, Desai TA.  PMID: 37476069; PMCID: PMC10354771.

22. Impact of interleukin-6 on T cells in kidney transplant recipients. Am J Transplant. 2022 12; 22 Suppl 4:18-27.Chandran S, Tang Q.  PMID: 36453710.

23. The dichotomous outcomes of TNFα signaling in CD4+ T cells. Front Immunol. 2022; 13:1042622.Skartsis N, Ferreira LMR, Tang Q.  PMID: 36466853; PMCID: PMC9708889.

24. Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans. Sci Transl Med. 2022 11 02; 14(669):eabo2628.Tang Q, Leung J, Peng Y, Sanchez-Fueyo A, Lozano JJ, Lam A, Lee K, Greenland JR, Hellerstein M, Fitch M, Li KW, Esensten JH, Putnam AL, Lares A, Nguyen V, Liu W, Bridges ND, Odim J, Demetris AJ, Levitsky J, Taner T, Feng S.  PMID: 36322627; PMCID: PMC11016119.

25. A Phase I/IIa study of autologous tolerogenic dendritic cells immunotherapy in kidney transplant recipients. Kidney Int. 2023 03; 103(3):627-637.Moreau A, Kervella D, Bouchet-Delbos L, Braudeau C, Saïagh S, Guérif P, Limou S, Moreau A, Bercegeay S, Streitz M, Sawitzki B, James B, Harden PN, Game D, Tang Q, Markmann JF, Roberts ISD, Geissler EK, Dréno B, Josien R, Cuturi MC, Blancho G, DIVAT consortium.  PMID: 36306921.