Diabetes Center researcher Allison Xu, PhD, is focused on understanding how the central nervous system regulates body weight and glucose levels. She studies how body weight is dependent on the brain sensing and responding to changes in energy stores in the body. Her exciting research often focuses on the hormone leptin and how it works in a critically important organ of the body, the liver.
The UCSF Pancreatic Islet Transplantation Program led by Andrew Posselt, MD, PhD, continues to be very active and, most importantly, very cutting edge. Not only does Dr. Posselt and his team efficiently and effectively harvest islets through their state-of-the-art islet isolation process, they are using new enzymes to ensure islet viability throughout the transplant process.
For relatives of people with type 1 diabetes who are not yet diagnosed, but who are at risk for type 1 diabetes, there are now promising clinical trials available. UCSF Pediatric Diabetes Program Director Stephen Gitelman, MD, suggests that all family members take a simple blood test which screens for the presence of diabetes-related autoantibodies that may appear years before type 1 diabetes develops.
The research group of Diabetes Center Director Matthias Hebrok, PhD, and collaborators at Texas A&M University, discovered that mesenchymal fetal tissue plays a fundamental role in the formation of insulin-producing beta cells. In lab animals, they found that the mesenchyme secretes chemicals that multiply and expand cells that are slated to become both hormone producing cells and beta cells.
Nearly a century has passed since the discovery of injectable insulin in the 1920s turned the tide on diabetes, helping to save countless lives. Today, even as research into the disease proceeds apace, the diabetes epidemic continues to grow. In California alone, an estimated 4 million people (one out of every seven adults) have diabetes, and the disease costs the U.S. health care system more than $200 billion annually.
In recognition of UCSF pediatrician and diabetologist Dr. Saleh Adi and his vision, passion and extraordinary skills in helping children with diabetes, an anonymous couple has made a transformational $10 million gift to help launch and operate the “best pediatric diabetes clinic on the west coast.”
Each year, California has more new cases of diabetes than any other state in the nation. Of the 4 million Californians with diabetes (1 in 7 adults), approximately 1.4 million are undiagnosed and unaware they have the disease. Additionally, it is estimated that 11.1 million Californians have prediabetes, a condition that increases risk for developing type 2 diabetes within 10 years.
It is with great sadness that we announce that our friend and colleague, John Baxter, MD, passed away on October 5th. Prior to his move to Methodist Hospital in Houston, John had been a member of the UCSF faculty for more than 30 years. He was the former Chief of the Division of Endocrinology and Metabolism and Director of the Metabolic Research Unit, the forerunner of the present Diabetes Center.
The Diabetes Teaching Center is proud to announce their new educational mobile app, Diabetes IQ. DiabetesIQ was created by the collaborative efforts of the University of San Francisco Diabetes Teaching Center and QuantiaMD. The mobile application, available for iOS and Android platforms, is an innovative new way for patients to explore their knowledge of the forms, progression, treatment, and complications of diabetes.
UCSF is a proud sponsor of the California Diabetes Summit, the only statewide public health conference that brings together California's preeminent diabetes prevention and control professionals, as well as leaders in policy, systems change, environmental approaches, health communications and health systems. Speakers include faculty members Dean Schillinger, MD, and Robert Lustig, MD. For more information, email
For relatives of people with type 1 diabetes who are not yet diagnosed, but who are at risk for type 1 diabetes, there are now promising clinical trials available. UCSF Pediatric Diabetes Program director Steve Gitelman, MD, suggests that all family members take a simple blood test which screens for the presence of diabetes-related autoantibodies that may appear years before type 1 diabetes develops.
We are pleased to report that the National Institutes of Health awarded Northern California's Kaiser Permanente's Division of Research a Center for Diabetes Translation, with UCSF serving as a key collaborator. As one of seven centers nationwide, the focus will be on diabetes prevention, diabetes health technology and diabetes disparities.
The Diabetes Teaching Center was named a Technical Innovation Finalist in the San Francisco Business Times Health Care Heroes Awards. The award was presented in recognition of the Teaching Center’s innovation in creating Diabetes Education Online, www.deo.ucsf.edu.