Publications

Our faculty members publish numerous articles in scientific journals.  These articles appear below and may also be accessed on the webpage of each faculty member.

Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, Howard E, Spiegelman BM, Seehra J, Lachey J. A Novel Therapeutic Approach to Treating Obesity through Modulation of TGFβ Signaling. Endocrinology. Tuesday, May 1, 2012
Shingo Kajimura, Ph.D.
Ohno H, Shinoda K, Spiegelman BM, Kajimura S. PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein. Cell Metab. Wednesday, March 7, 2012
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. Wednesday, January 11, 2012
Shingo Kajimura, Ph.D.
Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest. Tuesday, January 4, 2011
Shingo Kajimura, Ph.D.
Gaspar-Maia A, Alajem A, Meshorer E*, Ramalho-Santos M.* (2011) Open chromatin in pluripotency and reprogramming. Nat Rev Mol Cell Biol. 12:36-47
Miguel Ramalho-Santos, Ph.D., M.Sc.
Ohi Y, Qin H, Hong C, Blouin L, Polo JM, Guo T, Qi Z, Downey SL, Manos PD, Rossi DJ, Yu J, Hebrok M, Hochedlinger K, Costello JF, Song JS*, Ramalho-Santos M.* (2011) Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat Cell Biol. 13:541-9
Miguel Ramalho-Santos, Ph.D., M.Sc.
Koh FM, Sachs M, Guzman-Ayala M, Ramalho-Santos M.* (2010) Parallel gateways to pluripotency: open chromatin in stem cells and development. Curr Opin Genet Dev. 20:492-9
Miguel Ramalho-Santos, Ph.D., M.Sc.
Ramalho-Santos, M.* (2009) iPS cells: insights into basic biology. Cell 138: 616-8
Miguel Ramalho-Santos, Ph.D., M.Sc.
Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M.* (2009) Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature 460:863-8
Miguel Ramalho-Santos, Ph.D., M.Sc.
Ramalho-Santos, M.* (2004) Stem cells as probabilistic self-producing entities. Bioessays 26:1013-6
Miguel Ramalho-Santos, Ph.D., M.Sc.
Miguel Ramalho-Santos, Ph.D., M.Sc.
2. Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao XB, Horvath TL. (2010). Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. J Neurosci. 30(35): 11815-11825.
Allison Xu, Ph.D.
Su H, Marcheva B, Meng S, Liang FA, Kohsaka A, Kobayashi Y, Xu AW, Bass J, Wang X. (2010). Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice. Dev Biol. 339(1): 38-50.
Allison Xu, Ph.D.
Reed AS, Unger EK, Piper ML, Myers Jr. MG, Xu AW. Functional role of Socs3 up-regulation in hypothalamic leptin resistance and long term energy homeostasis. Diabetes. 2010. 59(4): 894-906.
Allison Xu, Ph.D.
Allison Xu, Ph.D.
Unger EK, Piper ML, Olofsson LE, Xu AW. Hypothalamic regulation of food intake by c-Jun-N-terminal kinase. Endocrinology, 2010. 151(2): 671-682.
Allison Xu, Ph.D.
Olofsson LE, Pierce AA, Xu AW. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proc Natl Acad Sci U S A. 2009. 106: 15932-37.
Allison Xu, Ph.D.
D. Han, A.G. Lerner, L. Vande Walle, J-P Upton, W. Xu, A. Hagen, B.J. Backes, S. A. Oakes, F.R. Papa IRE1-alpha Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates Cell 138, 562–575, August 7, 2009
Feroz Papa, M.D., Ph.D.
A. Trusina, F.R. Papa*, C. Tang* Rationalizing translation attenuation in the network architecture of the unfolded protein response Proc. Natl. Acad. Sci. U S A. 105(51):20280-5. Dec 23, 2008.
Feroz Papa, M.D., Ph.D.
Feroz Papa, M.D., Ph.D.
 
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