May 2013 eUpdate
UCSF's Leadership in Regenerative Medicine
Ever since Gail Martin, PhD, co-discovered embryonic stem cells in mice more than three decades ago, UCSF has been a leader in this promising area of research. In 2004, individual members of our Diabetes Center leadership joined the regenerative medicine crusade by supporting the efforts of a visionary member of our Leadership Council, Bob Klein, the architect of Prop 71 -- the $3 billion California Stem Cell Research and Cures Act. Historical advances continue to be made, as shared in a recent story, Nobel Prize Rockets Stem Cell Program to New Heights.
The legacy continues. Thanks in large part to funding provided by the California Institute for Regenerative Medicine (CIRM) -- the institution created by Prop 71, the Diabetes Center's Mark Anderson, MD, PhD, and Center Director Matthias Hebrok, PhD, have created the first functioning human thymus tissue derived from embryonic stem cells. This discovery is expected to generate new treatments for autoimmune diseases including type 1 diabetes, and improved outcomes for organ and tissue transplantation and cellular-based therapies. <Full Story> <Short Video>
Diabetes Education Online's New Translations in Chinese and Spanish
Thanks to generous private philanthropy, our award-winning educational website, Diabetes Education Online, was recently translated into both Chinese and Spanish, making quality online diabetes education available to millions of patients managing diabetes worldwide.
Developed by adult endocrinologist Martha Nolte Kennedy, MD, and her team at the UCSF Diabetes Teaching Center, Diabetes Education Online is a comprehensive diabetes self-management education program that covers the American Diabetes Association's recommended topics and more. The website mirrors the Diabetes Teaching Center's successful educational program given to thousands of UCSF patients over the last 30 years.
Pediatric to Adult Transition Program Launched at UCSF Madison Clinic
As part of the Diabetes Center’s mission to improve the quality of care for patients, the Madison Clinic for Pediatric Diabetes has implemented a program to assist older youth in their transition to adulthood. Funded by the UCSF Diabetes Family Fund, this “Transition Program” is designed to assist families and youth to be better prepared to take on their future needs in managing diabetes within the context of their new life -- whether it be in college, work, or in their own independent family life.
This innovative, groundbreaking clinical program is designed to improve the patient experience and enhance care for teens and young adults who must learn how to manage their own diabetes care as they become adults. It also assists parents in preparing for their child’s future transition into adulthood. This program was developed with feedback from adolescent, young adults and parents from the Madison Clinic to ensure that all future adult diabetes needs were met. <Full Story>
The Diabetes Center at UCSF is among the premier institutions for clinical trials of emerging therapies in diabetes. Numerous clinical trials in type 1 and 2 diabetes are now underway. Interested in participating? A sample of our trials is listed below.
TrialNet Natural History Study [Antibody Screening]. Seeking relatives of people with type 1 diabetes, 1 to 45 years of age
Type 1 Diabetes: An Oral Insulin Preventative Study. Seeking relatives of people with type 1 diabetes, 3 to 45 years of age
Type 1 Diabetes: Anti-CD3 mAB (Teplizumab) Preventative Study. Seeking relatives of people with type 1 diabetes, 8 to 45 years of age
Type 1 Diabetes: CTLA-4 lg (Abatacept) Preventative Study. Seeking relatives of people with type 1 diabetes, 6 to 45 years of age
Type 1 Diabetes: Evaluation of Residual Beta Cell Function and Immunologic Features in Patients with Longstanding Type 1 Diabetes. Seeking volunteers 8 years or older who have had type 1 diabetes for five or more years and have a hemoglobin A1c < 9.5%
Type 2 Diabetes: Paleolithic-Type Diets and Metabolic Control. Seeking volunteers 18 years of age and older with type 2 diabetes
Non-Diabetes: Motivational Physical Activity Education Study (mPED). Women between 25 and 69 years of age
Non-Diabetes: A Mobile Phone Based Diabetes Prevention Program (mDPP). Over 35 years of age, overweight, not physically active
APS1 and Autoimmune Disease. Seeking volunteers at least 6 weeks of age who have either autoimmune disease, have evidence of autoimmunity, have a family member with autoimmunity, or do not have autoimmune disease (healthy volunteer control)
For a list of all of our trials, visit the clinical trials section of our website, or Lorraine Stiehl..
Diabetes Center at UCSF
If you wish to receive more information about the UCSF Diabetes Center’s clinical and research programs, or would like to financially support one or more of these efforts, please contact Suzanne Ritchie at 415-476-6334. You may also visit our donation webpage and/or designate your donation to the program of your choice.
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