Type 1 Diabetes: Age 18 and up – Within Two Years of Diabetes Diagnosis


DRUG NAME: PF-06342674 (RN168)

Study Name: A Phase 1 Study of PF-06342674 in Adults with Type 1 Diabetes

Principal Investigator: Stephen E. Gitelman, MD

Who can sign up for this study? Volunteers must be at least 18 years old and have had diabetes for no more than 2 years. Women cannot be pregnant or breastfeeding.

What is this study about? The purpose of this research study is to learn about the effects of the study drug, PF-06342674 and to find the dose for treating T1DM.

What will happen in this study? All volunteers will undergo a screening visit where they will be asked questions about their medical history, undergo a physical exam, and provide blood and urine for tests.

Volunteers who qualify and are enrolled will receive a course of PF-06342674 injections or matching placebo injections.

All volunteers will be monitored for approximately 5 months. This will require several visits to UCSF for laboratory testing during this period. Blood will be drawn at each visit for lab work.

How long will this study last? Each volunteer will be followed for approximately 5 months.

Reimbursement: You will not be charged for any of the study treatments and may be eligible for reimbursement for your time and effort.

For more information please contact:

Kathleen Fraser, Diabetes Center at UCSF

Email: clinicalresearch@diabetes.ucsf.edu

Call toll-free: 1-844-T1D-UCSF