Publications

Our faculty members publish numerous articles in scientific journals. These articles appear below and may also be accessed on the webpage of each faculty member.

Klonoff, D.L., Barrett, B.J., Nolte, M.S., Cohen, R.M., Wyderski, R. Hypoglycemia following inadvertent and factitious sulfonylurea overdosages. Diabetes Care 18:563, 1995.

Martha Nolte Kennedy, M.D.

Roll, U., Turck, C.W., Gitelman, S.E., Rosenthal, S.M., Nolte, M.S., Masharani, U., Ziegler, A.G., Baekkeskov, S. Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients. Diabetologia 43: 598, 2000.

Martha Nolte Kennedy, M.D.

Nolte, M.S., "Insulin therapy in insulin-dependent (type I) diabetes mellitus." in Endocrinology and Metabolism Clinics of North America. June, 1992, p. 281 – 305.

Martha Nolte Kennedy, M.D.

Gehi, A.,Webb, A., Nolte,M., Davis,J. Treatment of systemic lupus erythematosus-associated type B insulin resistance syndrome with cyclophosphamide and mycophenolate mofetil. Arthritis and Rheumatism 48:1067, 2003.

Martha Nolte Kennedy, M.D.

Kim, S. K., Hebrok, M., Li, E., Oh, P., Schrewe, H., Harmon, E. B., Lee, J. S. and D. A.Melton. (2000) Activin receptor patterning of foregut organogenesis. Genes & Development 14, 1866-1871.

Matthias Hebrok, Ph.D.

Kim, S. K. and Hebrok, M. (2001) Intercellular signals regulating pancreas development and function. Genes & Development 15, 111-127.

Matthias Hebrok, Ph.D.

Pasca di Magliano, M., and M. Hebrok, (2003) Hedgehog signalling in cancer formation and maintenance. Nature Reviews Cancer (in press).

Matthias Hebrok, Ph.D.

Thayer, S. P., Pasca di Magliano, M., Heiser, P.W., Roberts, D. J., Nielsen, C. M., Lauwers, G. Y., Qi, Y.P., Gysin, S., Fernandez-del Castillo, F., Yajnik, V., Antoniu, B., McMahon, M., Warshaw, A. L., and M. Hebrok (2003) Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 2003 Oct 23;425(6960):780-2.

Matthias Hebrok, Ph.D.

Kawahira, H., Tzanakakis, E., Ma, N., McMahon, A.P., Chuang, P.-T., and M. Hebrok (2003) Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development (in press).

Matthias Hebrok, Ph.D.

Parangi, S., Dietrich, W., Christofori, G., Lander, E., & Hanahan, D. (1995). Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma. Cancer Research 55: 6071-6076.

Doug Hanahan, Ph.D.

Smith, K.M., Olson, D.C., Hirose, R. and Hanahan, D. Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance. In press.

Doug Hanahan, Ph.D.

Naik, P.N., Karrim, J., and Hanahan, D. (1996). The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors. Genes Dev. 10: 2105-2116.

Doug Hanahan, Ph.D.

Hanahan, D. and Folkman, J. (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.

Doug Hanahan, Ph.D.

Arbeit, J., Howley, P., and Hanahan. D. (1996). Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. PNAS 93: 2930-2935.

Doug Hanahan, Ph.D.

Kanaani, J., El-Husseini, A. E-D., Aguilera-Moreno, A., Diacovo, J. M., Bredt, D. S., and Baekkeskov, S A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. J. Cell Biol. 158, 1229-1238. 2002.

Steinunn Baekkeskov, Ph.D.

Jaume, J. C., Parry, S. L., Madec, A.-M., Sønderstrup, G., and Baekkeskov, S. Suppressive effect of glutamic acid decarboxylase 65-specific autoimmune B lymphocytes on processing of T cell determinants located within the antibody epitope. J. Immunology 169, 665-672, 2002.

Steinunn Baekkeskov, Ph.D.

Shi, Y., Kanaani, J., Menard-Rose, V., Ma, Y-H., Chang, P-Y, Hanahan, D., Grodsky, G., and Baekkeskov, S. Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. Am. J. Physiol. Endocrinol. Metab. 279, 684-694, (2000).

Steinunn Baekkeskov, Ph.D.

Roll, U., Turck, C.W., Gitelman, S.E., Rosenthal, S.M., Nolte, M.S., Masharani, U., Ziegler, A.-G., and Baekkeskov, S. Peptide mapping and characterization of glycosylation patterns of the glima 38 antigen recognized by autoantibodies in Type 1 diabetic patients. Diabetologia, 43, 598-608 (2000).

Steinunn Baekkeskov, Ph.D.

Schwartz, H., Chandonia, J-M., Kash, S. F., Tunnell, E., Domingo, A., Cohen, F., Banga, J. P., Madec, A.-M., Richter W., and Baekkeskov, S High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase. J. Mol. Biol. 287, 983-999 (1999).

Steinunn Baekkeskov, Ph.D.

Ashrafi, K., Chang, F. Y., Watts, J. L., Fraser, A. G., Kamath, R. S., Ahringer, J., and Ruvkun, G. (2003). Genome-wide RNAi analysis of C. elegans fat regulatory genes. Nature 421, 267-272.

Kaveh Ashrafi, Ph.D.