Publications

Our faculty members publish numerous articles in scientific journals.  These articles appear below and may also be accessed on the webpage of each faculty member.

Aanstad, P., Santos, N., Corbit, K. C., Scherz, P. J., Trinh, L. A., Salvenmoser, W., Huisken, J., Reiter, J.F., and Stainier, D. Y. (2009). The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Current Biology. 19 (12): 1034-9.
Jeremy Reiter, M.D., Ph.D.
Wong, S., and J. F. Reiter. (2008). The Primary Cilium: At the Crossroads of Mammalian Hedgehog Signaling. Current Trends in Developmental Biology. 85: 225-270.
Jeremy Reiter, M.D., Ph.D.
Corbit, K. C., Shyer, A. E., Dowdle, W. E., Gaulden, J., Singla, V., Chen, M. H., Chaung, P. T., and J. F. Reiter. (2007). Kif3a constrains b-catenin-dependent Wnt signaling through dual ciliary and non-ciliary mechanisms. Nature Cell Biology. 10 (1): 70-84.
Jeremy Reiter, M.D., Ph.D.
Ku G and McManus MT (2008). Exploiting small RNA pathways for gene therapy. Human Gene Therapy, REVIEW, 19(1):17-26.
Michael T. McManus, Ph.D.
Osokine I, Hsu R, Loeb G, McManus MT (2008). Unintentional miRNA ablation is a risk factor in gene knockout studies. PLoS Genetics, 15;4(2):34-36.
Michael T. McManus, Ph.D.
Cuellar T, Davis T, Loeb G, Nelson PT, Harfe, BD, Ullian E, McManus MT (2008). Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in absence of neurodegeneration. PNAS, 105(14):5614-9.
Michael T. McManus, Ph.D.
Bassik M, Lebbink R, Churchman LS, Ingolia NT, Patena W, LeProust EM, Patena W, Schuldiner M, Weissman JS, McManus MT (2009). Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods, e-published ahead of print.
Michael T. McManus, Ph.D.
Huang TH, Loeb GB, Hsu R, Heidersbach A, Brincat A, Lebbink RJ, McManus MT (2009). Upregulation of miR-21 by HER2/neu signaling promotes cell invasion. Journal of Biological Chemistry, 284 (27):18515-24.
Michael T. McManus, Ph.D.
Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, and Ramalho-Santos M (2009). Chd1 regulates open chromatin and pluripotency of ES cells. Nature, e-published ahead of print.
Michael T. McManus, Ph.D.
Miguel Ramalho-Santos, Ph.D., M.Sc.
M.S. Anderson , E. Venanzi, Z. Chen, S. Berzins, C. Benoist, and D. Mathis. The cellular mechanism of aire control of T cell tolerance. Immunity 23:227-239, 2005.
Mark Anderson, M.D., Ph.D.
J. DeVoss, Y. Hou, K. Johannes, W. Lu, G.I. Liou, J. Rinn, H. Chang, R.R. Caspi, L. Fong, and M.S. Anderson. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med, 203:2727-2735, 2006.
Mark Anderson, M.D., Ph.D.
J. Devoss., M.S.Anderson. Lessons on immune tolerance from the monogenic disease APS1. Curr Opin Genet Dev., 3:193-200, 2007.
Mark Anderson, M.D., Ph.D.
M.H. Cheng, A.K. Shum, and M.S. Anderson. What's new in the Aire? Trends in Immunology; 28:321-27, 2007.
Mark Anderson, M.D., Ph.D.
L. Zhang, J.M. Barker, S. Babu, M. Su, M. Stenerson, M. Cheng, A. Shum, E. Zamir, R. adolato, A. Law, G.S. Eisenbarth, and M.S. Anderson. A robust interferon immunassay that is highly specific for patients with Autoimmune Polyglandular Syndrome Type 1. Clinical Immunology, 125:131-137, 2007.
Mark Anderson, M.D., Ph.D.
M.A. Su, K. Giang, K. Zumer, H. Jiang, I. Oven, J.L. Rinn, J.J. Devoss, K.P. Johannes, W. Lu, J. Gardner, A. Chang, P. Bubulya, H.Y. Chang, B.M. Peterlin, and M.S. Anderson. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. J Clin Invest 118:1712-1726, 2008.
Mark Anderson, M.D., Ph.D.
J. Gardner, J. DeVoss, R. Friedman, D. Wong, K.P. Johannes, Y. Tan, H. Chang., M. Krummel., and M.S.Anderson. Deletional Tolerance Mediated by Extrathymic Aire-expressing Cells. Science 321:843-847, 2008.
Mark Anderson, M.D., Ph.D.
J. DeVoss, A.K. Shum, K.P. Johannes, W. Lu, A.K. Krawisz, T. Yang, N.P. LeClair, E. Strauss, and M.S. Anderson. Effector mechanisms of the autoimmune syndrome in the murine model of Autoimmune Polyglandular Syndrome Type 1. J Immunol 181:4072-4079, 2008.
Mark Anderson, M.D., Ph.D.
Travis MA, Reizis B, Melton AC, Masteller E, Tang Q, Proctor JM, Wang Y, Bernstein X, Huang X, Reichardt L, Bluestone JA, Sheppard D. Loss of integrin a v ß 8 on dendritic cells causes autoimmunity and colitis in mice. Nature 448:727-838, 2007.
Jeffrey A. Bluestone, Ph.D.
Tang, Q., Adams , J.Y., Tooley, A.J., Bi, M., Fife , B.T., Serra, P., Santamaria, P., Locksley, R.M., Krummel, M.F., Bluestone, J.A. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat. Immunol. 7:83-92, 2006.
Jeffrey A. Bluestone, Ph.D.
Travis MA, Reizis B, Melton AC, Masteller E, Tang Q, Proctor JM, Wang Y, Bernstein X, Huang X, Reichardt L, Bluestone JA, Sheppard D. Loss of integrin a v ß 8 on dendritic cells causes autoimmunity and colitis in mice. Nature 448:727-838, 2007.
 
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