New Scientific Resources Created to Expedite Research Progress
UCSF Diabetes Center researcher Michael McManus, PhD, and his colleagues at UCSF, the Gladstone Institute for Cardiovascular Disease, and Children's Hospital Oakland Research Institute, have created a new, publicly available resource that will help researchers understand the importance of certain genes in causing diabetes and other diseases. This resource consists of a library of gene-disrupting vectors that target and remove pieces of DNA that encode for microRNAs -- small bits of genetic material that regulate other genes. This new resource also includes new stem cell lines and new strains of animal models that are missing microRNAs. These tiny genes are thought to be important regulators of human disease.